Notwithstanding various treatments available to help smokers quit, there are just 2 prescribed quit smoking drugs that does not have nicotine as an ingredient. These nicotine-free stop smoking drugs are Zyban and Chantix. Most anti-smoking medications can be deemed nicotine replacement medicines, and are typically designed to move one’s addiction from cigarettes and tobacco to the nicotine replacement. Zyban, which contains Bupropion, is basically an antidepressant drug which was recently demonstrated to have nicotine antagonistic functions and have been applied as a quit smoking remedy. Whereas, Chantix, also known as Varenicline, is considered as a partial nicotine antagonist and is a newer addition to smoking cessation medications.